Fig. 3
From: Chromosomal instability in a patient with ring chromosome 14 syndrome: a case report
Giemsa-stained altered mitotic cells, sequentially studied by FISH using the TCL1 break-apart probe. These cells were harvested without colchicine block and KCl shock. A-D Two metaphase cells with chromosome compaction and distribution resembling those harvested with colchicine. E-H Metaphase cells displaying lagging chromosomes, excluding chromosome 14 and r(14). I-L Mitotic cells with multipolar-like configurations, also showing lagging chromosomes