Table 2 Detailed information about subgroups
From: Performance of cell free DNA as a screening tool based on the results of first trimester screening
FTS Risk Group | Subgroup (Risk Score) | Number of Cases | NIPT Positive (T21) | NIPT False Positives (T21) | NIPT Positive (T18) | NIPT False Positives (T18) | NIPT Positive (T13) | NIPT False Positives (T13) | NIPT Positive (SCAs) | NIPT False Positives (SCAs) |
|---|---|---|---|---|---|---|---|---|---|---|
Low Risk | risk < 1/1000 | 1150 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
1/1000 < risk < 1/300 | 393 | 4 (1%) | 1 (0.25%) | 2 (0.5%) | 2 (0.5%) | 2 (0.5%) | 2 (0.5%) | 38 (9.6%) | 38 (9.6%) | |
High Risk | 1/300 < risk < 1/11 | 118 | 18 (15.2%) | 2 (1.6%) | 5 (4.2%) | 3 (2.5%) | 3 (2.5%) | 1 (0.8%) | 24 (20.3%) | 18 (15.2%) |
1/10 < risk < 1/2 | 13 | 6 (46.1%) | 0 | 0 | 0 | 0 | 0 | 0 | 0 |